For nearly 2 decades, Alzheimer’s disease “genome-wide” association studies only covered the autosomes. Today, Belloy and colleagues unveil the X chromosome and prioritize SLC9A7 as a novel Alzheimer’s disease risk gene and potential drug target.
Halfway into 2024, The Belloy lab has welcomed its first four members: Danielle, Chenyu, Noah, and Katie! It was due time to celebrate this wonderful team with a great and tasty lunch!
Belloy and colleagues show that the impact of APOE genotype on Alzheimer’s disease is influenced by age, sex, race, ethnicity, and ancestry. These findings have significant implications for treatment-related decision-making and clinical trials.
As vice chair of the Sex and Gender Differences PIA, Michael Belloy, PhD had the opportunity to host a wonderful journal club session including a “meet the authors”. Papers covered how APOE and X chromosome variants contribute to sex dichotomy in cognition and brain function. The recording can be retrieved here: https://training.alz.org/nl/Research-Webinars
The Belloy lab is highly excited to announce it’s opening and joining the Neurogenomics and Informatics (NGI) center. We are now actively recruiting on multiple levels!